Application of the PET-CT method in the diagnosis and staging of chronic lymphocytic leukemia
DOI:
https://doi.org/10.53660/766.prw1927Palavras-chave:
Chronic Lymphocytic Leukemia, PET-CT, 18F-FDGResumo
Positron Emission Tomography (PET) combined with anatomical structural images from Computed Tomography (CT) is a technique belonging to nuclear medicine that consists of the morphofunctional evaluation, through the quantification of the cellular uptake of glucose analog molecules linked to radioactive compounds (18F-fluorodeoxyglucose), which represents the avidity glycolytic metabolism by the, tissues including neoplastic processes. In turn, the method can offer a great contribution in the differential diagnosis and staging of chronic lymphocytic leukemia (CLL), whose disease is characterized by the proliferation of type B lymphocytes in lymphoid tissues, bone marrow and peripheral blood. The objective of the study is to indicate the benefits of the PET-CT technique in the early detection of CLL and its respective staging, through a systematic literature review of a qualitative nature, using the databases SciELO e PubMed, whose triage of the articles was carried out using of the PRISMA protocol. PET-CT plays an essential role in the diagnosis of CLL and assessment of the potential for transforming the disease into Richer Syndrome, with a poor prognosis and the need to apply aggressive therapies.
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