Efficacy of nitenpyram on the treatment of tungiasis in dogs from brazilian southern amazonic region
DOI:
https://doi.org/10.53660/604.prw1702dResumo
Tungiasis is a zoonotic skin disease caused by the penetration of the female flea of Tunga penetrans into the skin of many mammal hosts. Among the hosts, domestic, synanthropic and sylvatic animals serve as reservoirs. However, the dogs are considered the main source of human infestation in rural and endemic communities. The aim of this study was to evaluate the tungicidal efficacy of nitenpyram for the treatment of tungiasis caused by Tunga penetrans in naturally infested dogs from brazilian amazonic region. Twelve dogs presenting from three to fifty-three viable lesions received one dose of nitempyram. The animals received dosages according to the manufacture’s recommendation. The criteria used to determine the drug efficacy were the number of viable lesions after treatment. These were quantified at 3, 7- and 14-days post-treatment. According to the results, the efficacy of Nitempyram was 92,20%, 88,07% and 66,06% in the 3, 7 and 14-days post-treatment.
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CARVALHO, R. W; ALMEIDA, A. B. DE .; BARBOSA-SILVA, S. C.; AMORIM, M.; RIBEIRO, P. C.; SERRA-FREIRE, N. M.. The patterns of tungiasis in Araruama township, state of Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, v. 98, p. 31-36, 2003.
CHATELLIER, K. Nitenpyram. Compendium on Continuing Education for the Practicing Veterinarian, v. 23, n. 8, p. 748-749, 2001.
DOS SANTOS, K. C.; CHIUMMO, R. M.; HECKEROTH, A. R.; ZSCHIESCHE, E.; BRANDÃO GUEDES, P. E.;; HARVEY, T. V.; DE JESUS, A. V.; DA PAIXÃO SEVÁ, A.; DE OLIVEIRA, J. T. S.; DOS SANTOS FREIRE, Z.; KRÜCKEN, J.; DE ALMEIDA BORGES, F.; VON SAMSON-HIMMELSTJERNA, G.; ALBERTO CARLOS, R. S. Efficacy of oral fluralaner (Bravecto) against Tunga penetrans in dogs: A negative control, randomized field study in an endemic community in Brazil. PLoS neglected tropical diseases, v. 16, n. 3, e0010251, 2022.
EISELE, M.; HEUKELBACH, J.; VAN MARCK, E.; MEHLHORN, H.; MECKES, O.; FRANCK, S.; FELDMEIER, H. Investigations on the biology, epidemiology, pathology, and control of Tunga penetrans in Brazil: I. Natural history of tungiasis in man. Parasitology Research, v. 90, n. 2, p. 87-99, 2003.
GATTI, F.R.; OLIVEIRA, C.M.; SERVILHA, T.R.; SANCHEZ, A.P.. Tungíase disseminada tratada com ivermectina. Anais Brasileiros de Dermatologia, v. 83, p. 339-342, 2008.
HARVEY, T. V., HEUKELBACH, J., ASSUNÇÃO, M. S., FERNANDES, T. M., DA ROCHA, C. M. B. M., & CARLOS, R. S. A. Seasonal variation and persistence of tungiasis infestation in dogs in an endemic community, Bahia State (Brazil): longitudinal study. Parasitology Research, v. 118, n. 6, p. 1711–1718, 2019.
HARVEY, T. V.; HEUKELBACH, J.; ASSUNÇÃO, M. S.; FERNANDES, T. M.; DA ROCHA, C. M.; CARLOS, R. S. Canine tungiasis: High prevalence in a tourist region in Bahia state, Brazil. Preventive veterinary medicine, v. 139, p. 76-81, 2017.
HOVDA, L. R.; HOOSER, S. B. Toxicology of newer pesticides for use in dogs and cats. The Veterinary Clinics: Small Animal Practice, v. 32, n.2, p. 455 – 467, 2002.
KLIMPEL, S.; MEHLHORN, H.; HEUKELBACH, J.; FELDMEIER, H.; MENCKE, N. Field trial of the efficacy of a combination of imidacloprid and permethrin against Tunga penetrans (sand flea, jigger flea) in dogs in Brazil. Parasitology Research, v. 97, n. 1, p. S113-S119, 2005.
MUTEBI, F.; KRUCKEN, J.; FELDMEIER, H.; WAISWA, C.; MENCKE, N.; VON SAMSON-HIMMELSTJERNA, G. Tungiasis-associated morbidity in pigs and dogs in endemic villages of Uganda. Parasit. Vectors, v. 10, n. 10, p. 1-18, 2016b.
MUTEBI, F.; VON SAMSON-HIMMELSTJERNA, G.; FELDMEIER, H.; WAISWA, C.; BUKEKA MUHINDO, J.; KRÜCKEN, J. Successful treatment of severe Tungiasis in pigs using a topical aerosol containing Chlorfenvinphos, Dichlorphos and gentian violet. PLoS neglected tropical diseases, v. 10, n. 10, p. e0005056, 2016a.
OLIVEIRA, I. S.; MOREIRA, B. S. V.; PEREIRA, S. O.; CASTRO, A. S.B.; MOREIRA, T.R.; SANTANA, L.A. Tungíase Atualidades clínicas, vol. 102, nº 6, Viçosa, 2014.
PILGRIM RLC. 1993. An instance of tungiasis in New Zealand. New Zealand Medical Journal, 106, 180.
SAMPAIO, I. B. M. Estatística Aplicada à Experimentação Animal. 2ª ed., Belo Horizonte: Fundação de Ensino e Pesquisa em Medicina Veterinária e Zootecnia, 2002.
SANUSI, ID; BROWN, EB; SHEPARD, TG; GRAFTON, WD. Tungiasis: report of one case and review of 14 reported cases in the United States. J Am Acad Dermatol, v. 20, p. 941- 944, 1989.
SCHENKER, R.; TINEMBART, O.; MARNETT, S.H.; WHITE, S. W. A brief introduction to nitenpyram: a new systemic flea adulticidal for cats and dogs. Compendium on Continuing Education for the Practicing Veterinarian., v.23, p. 4-6, 2001.
VERALDI S, CAMOZZI S, SCARABELLI G. Tungiasis presenting with sterile pustular lesions on the hand. Acta Dermato venereologica, v. 76, p. 495, 1996
VIESTEL, M.A.D.;DA SILVA, M.B.. Tungíase em cão: Relato de caso. Jornal Brasileiro de Ciência Animal, v. 5, n. 9, p. 313 – 319, 2012.
