Antimicrobial packaging based on molecular docking of natural products
Embalagens antimicrobianas baseadas em docking molecular de produtos naturais
DOI:
https://doi.org/10.53660/PRW-2493-4518Palavras-chave:
Molecular docking, Food packaging, Antimicrobial potential, Shelf life, Docagem molecular, Embalagem de alimento, Potencial antimicrobiano, Vida útil, Acoplamento molecularResumo
For a long time, studies on food packaging focused on antimicrobial agents, without, however, explaining the mechanisms. Therefore, in this analysis and opinion text, we approach the promising scenario, regarding the use of molecular docking techniques in the development of antimicrobial packaging. Molecular docking was identified as an important guidance tool, showing researchers which molecules had effective antimicrobial activity and their mechanisms. Furthermore, based on molecular docking studies, researchers were able to optimize in vitro and in vivo antimicrobial experiments. The targeted approach was efficient in developing antimicrobial packaging, which increased the shelf life of several foods. We consider molecular docking an indispensable tool for studies on antimicrobial packaging and a promising field of research.
Keywords: Molecular docking; Food packaging; Antimicrobial potential; Shelf life; Molecular docking.
Durante muito tempo, os estudos sobre embalagens de alimentos focaram-se nos agentes antimicrobianos, sem, no entanto, explicar os mecanismos. Portanto, neste texto de análise e opinião, abordamos o cenário promissor, no que diz respeito à utilização de técnicas de docking molecular no desenvolvimento de embalagens antimicrobianas. O docking molecular foi identificado como uma importante ferramenta de orientação, mostrando aos pesquisadores quais moléculas tinham atividade antimicrobiana eficaz e seus mecanismos. Além disso, com base em estudos de acoplamento molecular, os pesquisadores conseguiram otimizar experimentos antimicrobianos in vitro e in vivo. A abordagem direcionada foi eficiente no desenvolvimento de embalagens antimicrobianas, o que aumentou a vida útil de diversos alimentos. Consideramos o docking molecular uma ferramenta indispensável para estudos sobre embalagens antimicrobianas e um campo de pesquisa promissor.
Palavras-chave: Docagem molecular; Embalagem de alimentos; Potencial antimicrobiano; Vida útil; Acoplamento molecular.
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