Carbon quantum dots of Moringa oleifera with bactericidal action
DOI:
https://doi.org/10.53660/1654.prw3237Palavras-chave:
Nanotecnologia, Oxigênio singleto, Drogas, SaúdeResumo
In this work, carbon quantum dots (CQDs) were synthesized using a hydrothermal reactor. The precursor for the CQDs was Moringa oleifera seed oil, extracted using a 1:8 ethanol-to-mass ratio through ultrasound-assisted extraction (50 ºC, 30 min). The extract was then purified using a rotary evaporator (50 ºC, 50 rpm) to remove the solvent, followed by centrifugation (12,000 rpm, 10 min). Subsequently, the oil was transferred to a Teflon-lined capsule within a stainless-steel reactor and heated in a muffle furnace (210 ºC, 24 h). The synthesized CQDs were then centrifuged (12,000 rpm, 10 min) and filtered through a 0.22 μm membrane. These CQDs exhibited high fluorescence and, when activated photodynamically with white visible light, showed the ability to inhibit the growth of the Gram-positive bacterium Staphylococcus aureus, a common cause of skin infections. In recent decades, the inappropriate use of antibiotics has led to increased bacterial resistance, resulting in higher mortality rates in humans and animals. Therefore, the development of nanomaterials with antimicrobial properties, through a simple, cost-effective, and sustainable route, is essential for public health and safety.
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