Chemical composition and antimicrobial activity of Cordia globosa (JACQ.) essential oil against Staphylococcus aureus
DOI:
https://doi.org/10.53660/1387.prw2913Palavras-chave:
Boraginaceae, C. globosa, Essential oil, Caryophyllene, Anti-biofilmResumo
Cordia globosa (Jacq.), conhecida como "maria preta" na região Nordeste do Brasil, é uma planta de ampla utilização no tratamento de doenças gastrointestinais. Este trabalho teve como objetivo obter o perfil químico do óleo essencial da parte aérea de C. globosa, atividade antimicrobiana e antibiofilme contra Staphylococcus aureus. Nas análises de GC/MS foram detectados 47 compostos, dos quais monoterpenos 17,74%, monoterpenos oxigenados 6,84%, sesquiterpenos 40,50%, sesquiterpenos oxigenados 29,87%. Óxido de cariofileno 13,04%, β-Elemeno 12,30% e E-cariofileno 10,13%. Nos resultados, a CIM e o CBM foram de 1 mg/mL e 8 mg/mL, respectivamente. A ação antibiofilme foi confirmada para reduzir a biomassa do biofilme de S. aureus em até 97% entre concentrações de 2mg/mL e 4mg/mL. O óleo essencial de C. globosa demonstrou ser um antibiótico promissor contra S. aureus.
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