Anaplasma marginale transplacental transmission in a calf: clinical, anatomopathological, and molecular reports

Autores

  • Maria Roméria da Silva Department of Biochemistry and Molecular Biology, Universidade Federal de Viçosa, Brazil
  • Vanessa Isabel Leal Salvador Bizinotto Carqueijeiro Bastos Universidade de Uberaba, Brazil
  • Lincoln Herbert de Resende Junior Universidade de Uberaba, Brazil
  • Luiz Flávio Nepomuceno do Nascimento Universidade de Uberaba, Brazil
  • Guilherme Costa Venturini Universidade de Uberaba, Brazil
  • Luiza de Oliveira Possa Department of Biochemistry and Molecular Biology, Universidade Federal de Viçosa, Brazil
  • Thierry Grima de Cristo Department of Veterinary Medicine, Universidade do Estado de Santa Catarina, Brazil
  • Renata Assis Casagrande Department of Veterinary Medicine, Universidade do Estado de Santa Catarina, Brazil
  • Endrigo Gabellini Leonel Alves Universidade de Uberaba, Brazil
  • Isabel Rodrigues Rosado Universidade de Uberaba, Brazil
  • Eustáquio Resende Bittar Universidade de Uberaba, Brazil
  • Tiago Antônio de Oliveira Mendes Department of Biochemistry and Molecular Biology, Universidade Federal de Viçosa, Brazil
  • Joely Ferreira Figueiredo Bittar Universidade de Uberaba, Brazil

DOI:

https://doi.org/10.53660/1492.prw3026

Palavras-chave:

Anaplasmosis, Bovine, Congenital Anaplasmosis

Resumo

Bovine anaplasmosis is caused by obligate intracellular rickettsia Anaplasma marginale transmitted by ticks Rhipicephalus microplus, hematophagous flies, and/or iatrogenically. Transplacental transmission is possible but sub-reported. In this context, the present work aimed to report a case of a calf that was born with anemia, jaundice, and neurological problems. A calf blood smear showed intraerythrocytic inclusion of A. marginale. Accordingly, the animal was treated with oxytetracycline but died three days after the start of treatment. The necropsy revealed conjunctival and subcutaneous jaundice, splenic congestion and distension, and an intensely yellow liver were noted. Histopathology showed moderate, multifocal hepatocellular degeneration, diffuse and marked cholestasis, and histiocytic necrotizing encephalitis. A. marginale infection was confirmed by PCR, and real-time PCR (qPCR). qPCR analysis showed that 3.3% of the erythrocytes in the calf's blood sample were parasitized. Thus, here we report a case of transplacental transmission A. marginale in a newborn calf.

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Referências

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Publicado

2023-12-07

Como Citar

da Silva, M. R., Bastos, V. I. L. S. B. C. ., Resende Junior, L. H. de ., Nascimento, L. F. N. do, Venturini, G. C. ., Possa, . L. de O. ., Cristo, T. G. de ., Casagrande, R. A. ., Alves, E. G. L. ., Rosado, I. R. ., Bittar, E. R. ., Mendes, T. A. de O. ., & Bittar, J. F. F. . (2023). Anaplasma marginale transplacental transmission in a calf: clinical, anatomopathological, and molecular reports. Peer Review, 5(25), 307–319. https://doi.org/10.53660/1492.prw3026

Edição

v. 5 n. 25 (2023)

Seção

Artigos